Gold-Nano Blog / Gold Nanoparticle Cancer Research News #2
Originally Posted on 11/05/2017 @ 2:36 pm
Last Edited on 11/06/2017 @ 9:09am
by Steven Warrenfeltz
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This is the second update, of many, that will be written to keep you up-to-date on Gold Nanoparticle Cancer Research, one of the most promising cancer treatments in the research pipeline.
When we think of today's traditional methods of treating cancer, we think "chemo and/or radiation therapies."
What else comes to mind when we think of today's traditional methods of treating cancer?
Answer: discomfort, pain, and mortality...This shouldn't be the case.
Medicine should heal, not hurt an individual, we need to get out of the 20th-century's ways of treating cancer, and start using 21st-century methods to treat cancer.
Gold Nanoparticles are inert, and research studies have proven that they can be made to only attack and kill cancer cells, so there are no life-threatening side-effects associated with this research.
Gold Nanoparticle Cancer Research has repeatedly shown, in study after study, that it should be one of the 21st century's better ways of treating cancer.
In this report, you'll find summaries of the most promising and compelling studies in regards to gold nanoparticle medical research.
Below is a glimpse into what you'll find in this issue:
The article shines the light on some interesting elemental facts about gold; we all know that gold in its bulk form cannot be magnetized and does not tarnish.
But, did you know that gold nanoparticles are magnetic, and the property that keeps gold from tarnishing, in its bulk-form, helps to make its nano form inert? (the latter fact is not stated in the article)
These two characteristics of gold nanoparticles are just a sample of the unique properties that make them a great way to treat cancer.
Below is an excerpt from the article:
Magnetism is caused by unpaired electrons surrounding the atoms of the material.
Due to a quantum mechanical property called “spin”, unpaired electrons induce a magnetic dipole (like the two poles of a bar magnet).
However, electrons often like to team up in pairs, and the opposing spin of the two electrons cancels out the magnetic effect.
But in bulk gold, these unpaired electrons can be shared between atoms, allowing them to find a buddy and form a pair.
This means that metallic gold has no unpaired electrons, and it does not display classical magnetism. "Magnetic gold is evidence of relativity, study finds." - Joel F. Hooper, Cosmos Magazine
The article goes on to explain how gold atoms and electrons work and how the unique interaction of gold's electrons, from one atom to another, give it its characteristics in bulk and nano form.In addition, the conclusion of the article explains how gold nanoparticles get their magnetic properties in relation to Einstein's 'Theory of Relativity.' "Magnetic gold is evidence of relativity, study finds." - Cosmos Magazine
At Northwestern University, some hope has risen for those who have Glioblastoma, a new human trial is being conducted for this type of cancer.
The research involves attaching strands of RNA (RiboNucleic Acid), programmed to kill cancer, on gold nanoparticles.
In the article, Andrew Lee, Ph.D., a Northwestern Medicine researcher, stated the following about using gold nanoparticles in these human trials.
“There’s a bunch of challenges to delivering that molecule to the right place in a disease setting,” said Andrew Lee, Ph.D., a Northwestern Medicine researcher.
That’s where the nanoparticles shine. Packed with short strands of RNA – poised to deliver a deadly message to cancer cells — the loaded spheres move freely through the bloodstream without notice or reaction. In animal studies, they crossed the protective blood-brain barrier then penetrated tumor cells – ultimately sparking cell death.
“It really is the role of the size of the nanostructure as well as the density and exactly how the molecules are presented by the nanostructure that really give it an advantage in crossing each of those barriers,” Lee said. New clinical trial offers hope to patients with glioblastoma - Katharin Czink and Dina Bair, WGNTV (Chicago, Illinois)
If you have this form of cancer or know someone who is fighting Glioblastoma, there are links at the bottom of the WGNTV article that will give you information about enrollment, and as of this writing, it is still possible to be apart of this research.
This article offers an in-depth view of how researchers are learning how gold nanoparticles can help chemotherapy do its intended primary goal: To kill cancer while not harming the patient.
The excerpt below talks about how gold nanoparticles and targeted chemotherapy, also called 'Nanotherapeutics' is giving researchers new hope towards making chemotherapy drugs more effective.
In 2014, he and collaborators demonstrated that gold nanoparticles could be used to 'smuggle' chemotherapy drugs into cancer cells in glioblastoma multiforme, the most common and aggressive type of brain cancer in adults, which is notoriously difficult to treat.
The team engineered nanostructures containing gold and cisplatin, a conventional chemotherapy drug. A coating on the particles made them attracted to tumour cells from glioblastoma patients, so that the nanostructures bound and were absorbed into the cancer cells.
Once inside, these nanostructures were exposed to radiotherapy. This caused the gold to release electrons that damaged the cancer cell's DNA and its overall structure, enhancing the impact of the chemotherapy drug.
The process was so effective that 20 days later, the cell culture showed no evidence of any revival, suggesting that the tumour cells had been destroyed. How to train your drugs: nanotherapeutics - Medical Xpress
Recently, the National Science Foundation awarded Dr. Andy Chong, a University of Dayton researcher, $302,700 to create the next generation of pulsed lasers for hospitals and clinics.
He is working on lasers that generate visible wavelengths called 'pulsed fiber lasers,' they are less bulky than the medical lasers of today, and they are less expensive and easier to use.
These new lasers would also be more reliable than today's medical lasers and could be used for micro-surgeries, and work in conjunction with gold nanoparticles to kill cancer cells.
Dr. Andy Chong stated the following about the new laser he is working on:
“For medical purposes, we do believe the mode-locked fiber lasers are the future,” he said. “But for now, the visible wavelength laser is not directly available from mode-locked lasers. You have to start with the laser and convert to the visible wavelength. What I’m suggesting is we can build a laser that can generate visible light and make it readily available for medical applications in a way that is cheaper and more reliable.” - Dr. Andy Chong Laser Focused Research - University of Dayton
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Thank You for your Time.
Take Care & God Bless,