Gold-Nano Blog / Gold Nanoparticle Cancer Research News #4





Gold Nanoparticle Cancer Research News 
#4


Originally Posted on 01/29/2018 @ 5:02 pm

Last Updated and Edited on 01/31/2018 @ 2:16 pm

by Steven Warrenfeltz


Subscribe to this Blog

 Subscribe by RSS Feed




Gold Nanoparticles are inert, research studies have repeatedly proven that they only hurt cells they are made to attack, which are cancer cells, so there are no life-threatening side-effects associated with this research. 

Gold Nanoparticle Cancer Research News #4

In this report, you'll find summaries of the most promising and compelling studies, since late November of 2017, in regards to gold nanoparticle medical research.


Below is a glimpse into what you'll find in this issue:


  • Researchers at the University of Texas are using super computers to develop a cancer fighting 'Golden Pill'

  • Washington State University professor develops a new gold-platinum nanoparticle to fight cancer.

  • CRISPR-Cas9, Chinese scientists find more proof that gold nanoparticles should be used to deliver the genome-editing tool.












Designing a Golden Pill...

Researchers out of the University of Texas are trying to figure out the best way to developing a microscopic golden nano pill that will kill cancer cells.

In the study, researchers are using supercomputers at the Texas Advanced Computing Center at the University of Texas, as well as supercomputers in San Diego, California, to test how the gold pills would interact inside the body before they create them in the lab.

gold pill

The goal was to develop a golden nano pill that would navigate through the bloodstream, find cancer cells, then release its payload of cancer-killing drugs when infrared light was shown them.

To clarify, these pills won't be swallowed, nanoparticles are a hundred thousand times smaller than a human hair, instead, large quantities of these gold nano-pills will be injected into a patient's body.

In the article: Dr. Zhenpeng Qin, an assistant professor of Mechanical Engineering and Bio-engineering at the University of Texas at Dallas, stated the following about why they are using supercomputers in the development of these pills:

"A lot of people make nanoparticles and observe them using electron microscopy," Qin said. "But the computations give us a unique angle to the problem. They provide an improved understanding of the fundamental interactions and insights so we can better design these particles for specific applications."  Zhenpeng Qin - assistant professor of Mechanical Engineering and Bioengineering at the University of Texas at Dallas

The article goes on to state that Dr. Qin and the research team are testing different combinations of gold nanoparticles, including grouping or compacting gold nanoparticles together to enhance their collective attributes.

See the full article here Designing a golden nanopill - PHYS.ORG



Researchers use
Gold & Platinum Nanoparticles
to Fight Cancer


In this next study, researchers at Washington State University have developed nanoparticles made of gold and platinum to enhance their tumor-killing properties when heated.

gold and platinum

In this study, the researchers targeted the mitochondria of the cancer cell. 

Mitochondria are organelles found in cells, and their primary function is to produce energy for the cell, meaning that if the mitochondria are destroyed, the cell cannot survive.

The researchers used highly porous, core-shell gold-platinum nanoparticles that have a high surface area, which allowed them to deliver more cancer-killing drugs to the tumor.

Once the Au-Pt nanoparticles were inside the cancer cell's mitochondria, the researchers used a cancer treatment called Photodynamic Therapy (PDT) to activate them.

Photodynamic therapy (PDT) is a treatment that uses a drug called a photosensitizer and light to treat cancer.

When the light of the photodynamic therapy was shown on the gold-platinum nanoparticles, they released the photosensitizing drug, which created a catalytic reaction releasing oxygen through 'Reactive Oxygen Species' (ROS) that killed the cancer cell.

In addition, the researchers found that the gold-platinum nanoparticles enhanced the reaction inside the cell's mitochondrial by creating an ROS burst, making the Photodynamic Therapy (PDT) more lethal to the cancer cells.

In conclusion, the researchers found that gold-platinum nanoparticles made Photodynamic Therapy (PDT) more effective at killing cancer cells.

The lead researcher Annie Du, a professor in the School of Mechanical and Materials Engineering, stated the following about the results of the study:

"The new procedure, if approved for use, will mean fewer side effects for cancer patients." and "Ours is a targeted system, we increase drug concentration in the cancer cell itself, not in other parts of the body. This means physicians can prescribe smaller amounts of drugs."  - Annie Du, research professor in WSU’s School of Mechanical and Materials Engineering


See the full article here: WSU researchers use gold to target, kill cancer cells with less drugs by Siddharth Vodnala, intern, Voiland College of Engineering and Architecture - WSU News




cancer research






Gold Nanoparticles for the Delivery of CRISPR-Cas9

CRISPR stands for (Clustered Regularly Interspaced Short Palindromic Repeats), it is a genome-editing tool that splices then edits DNA.

It inhibits bad genes by removing a defective DNA strand and replacing it with a corrected strand of DNA code.

CRISPR-Cas9 has had lots of good results in several 'in vitro' or in the lab cancer research studies, but one big problem for this research that the genome-editing tool has a problem with is getting to its expected destination in a living specimen.

Plus, researchers have found out that the longer the CRISPR-Cas9 DNA-editing-tool hangs around in the body, the more it becomes a threat to the body because it could make unwanted 'edits.'

The last research study in this GNP Cancer Research News Report comes out of Beijing, China, at its National Center for NanoScience and Technology.

The researchers noted that they chose gold nanoparticles because they can be easily modified for various biological molecules.

In the study, once the gold nanoparticles found their targets, lasers were used to separate the CRISPR-Cas9 gene-editing tool from its nano-gold delivery vehicle.

When the separation occurred, this enabled the CRISPR-Cas9 gene editing to knockout of the targeted gene killing the cancer cells and inhibiting tumor growth.

The study has provided more positive results for using Gold Nanoparticles as CRISPR-Cas9's delivery system.

Plus, the research notes that gold nanoparticles add a complementary factor to aiding CRISPR-Cas9 by acting as a thermo-therapeutic agent.

The following is stated about the findings of the study:

“In summary, this relatively simple design using gold nanoparticles, peptides, and lipids assembled into a sophisticated multifunctional carrier/release system could serve as a multifunctional delivery platform for various aspects of gene therapy.” 

See the full article here: Gold Nanoparticles for the Delivery of CRISPR-Cas9 Therapeutics - ChemistryViews

Furthermore, The Director of NIH (National Institute of Health) recently wrote in his blog some encouraging words about using Gold Nanoparticles as the delivery system for CRISPR-Cas9.

You can see what the Director of NIH wrote here: Gene Editing: Gold Nanoparticle Delivery Shows Promise - National Institute of Health’s - ‘Director’s Blog.’







One last thing...



Thank You for your Time.

Take Care & God Bless,

Steve




Other pages, on this Guide, that you
may like...













SD Bullion

Bretton Woods

Establishing the Gold Standard of the

20th Century

Bretton Woods



Johnson Matthey

Bullion Refiner

Johnson Matthey

SilverGoldBull




Walmart












Home Page

FBIG - Home Page Screenshot

with Bullion Market News









Return from this

Gold Nanoparticle Cancer Research
News Update #4

and visit the

Main Blog page







Free Bullion Investment Guide







Free-Bullion-Investment-Guide "Search"
search engine by freefind advanced


Search - Magnify Glass






Free Bullion Investment Guide



Affiliate Links - Disclosure


Buy American Silver Eagle Coins



Donate through
PayPal or Credit Card


Thank You for
Your Support





Free Bullion Investment Guide



search

   Search the Guide

search engine by freefind advanced




recent guide updates

Daily

Bullion News on the Homepage



November 2024

Newsletter




Re-written

Gold Buying Guide

Gold Buying Guide



2023

Austrian Philharmonic Silver bullion coin

Mintage Figures




2023

Gold Austrian Philharmonic bullion coin

Mintage Figures




2023

Austrian Philharmonic Platinum bullion coin

Mintage Figures




Re-written

The Royal Mint &
United Kingdom Bullion Coins

Royal Mint - The Original Maker



Updated

Numismatic & Bullion Auctions page

Auctions page - Going, Going...



Updated

Gold Sovereigns

2024 Full Gold Sovereign - King Charles
2024 Full Gold Sovereign - King Charles - reverse side





Archangel Raphael
~
The Angel of Healing

ArchAngel Raphael - 05



Cancer Awareness Information & Resources

Cancer Awareness Month Ribbon with FBIG Gold-Nano Logo



Help Us Expand our Audience by forwarding our link

www.free-bullion-investment-guide.com.

Thank You!



November

Best News

Royal Canadian Mint revenue hits $252.7m in Q3 despite bullion slump - BPM

Graphic: Visualizing the Price of Bitcoin vs. Gold Over Time - Visual Capitalist

At These Levels, Buying Silver Is Like Getting It At $5 In 2003 - Hubert Moolman

Video: Why is Gold Still Undervalued - The New Gold Playbook - Precious Metals Summit Zurich 2004

China Discovers Massive Gold Reserves in Hunan - Greek Reporter

Fake Bullion: Sound Test: How to Detect Real & Fake Gold Maple Leaf bullion coins - Sound Money Metals (YouTube)

Crypto vs. Gold - The Gold Report

Video: Goldman's Dart Says Gold Could Hit $3,000 an Ounce Next Year - Bloomberg TV

Graphic: Visualizing the Gold-to-Silver Ratio Since 1869 - Visual Capitalist

Silver Global Industrial Demand on Track for a New Record High in 2024 - The silver market is set to see a sizeable structural deficit for the fourth consecutive year - The Silver Institute

Video: Will Rising Global Debt Boost Gold? - Bloomberg/CMEgroup

Why Austrian Business Cycle Theory Is Better than Keynesianism - The Cobden Centre

Top 5 Palladium and Platinum Countries by Production - Investing News

Video: Yvonne Blaszczyk of BMG Group: Global Gold Rush is On — BRICS Takeaways,
US Election Impact
 - Investing News Network (INN)

Gold Nanoparticle Cancer Research

Tiny Gold Radiators Fry Bacteria on Implants - AZOnano

Gold Outshines Platinum in Cancer Fight - Science Blog

The gold standard: Researchers enhance cardiology imaging by using gold nanoparticles - PHYS.org


All Articles were Originally Posted on the Homepage