Gold Nanoparticle Cancer Research News
#5

Originally Posted on 02/20/2018 @ 4:15 pm

by Steven Warrenfeltz

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Hello,

Gold Nanoparticle Cancer Research is one of the most promising cancer treatments that are in the research pipeline.

For the seven years, I've been helping people understand how gold nanoparticles offer a better way to treat cancer than the methods we are using today, most notably 'traditional chemo and traditional radiation therapies.'

One of the biggest setbacks of today's cancer-fighting treatments is the fact of they have to be administered in very large doses for them to be effective at killing cancer.

The result usually comes with a lot of pain in the form of terrible side effects because these drugs don't only attach the cancer cells, they attack healthy cells too.

Gold Nanoparticles are inert and research studies have repeatedly proven that they only attack the cancer cells, which means there are no life-threatening side-effects associated with this research.

This is the guide's fifth issue of the Gold Nanoparticle Cancer Research News Report, it covers the latest GNP cancer research that's been released over the last two weeks.

Below is a glimpse into what you'll find in this issue:

How Gold Nanoparticles killed Cancer Cells without Any assistance
Georgia Tech uses 'Hairy' Gold Nanoparticles to kill cancer
University of Texas Researchers learn how Gold Nanoparticles move in the Kidneys to help create better kidney disease fighting treatments
International Joint Research Group use Gold Nanoparticles to send two different cancer fighting drugs to kill cervical cancer cells.

Note:

All of the articles below have been summarized to make the subject matter more understandable, at the bottom of each summary you'll find direct links to the original articles or research report.

Gold Nanoparticles Destroy Breast Cancer Cells...Alone

In all honesty, I had to re-read several paragraphs in this first article because in almost every research study that I have read about gold nanoparticles they have been used in conjunction with another medium to kill cancer.

However, in this six-year study from the Autonomous Metropolitan University in Mexico City, researchers killed breast cancer cells using only gold nanoparticles.

In the study, researchers applied gold nanoparticles to breast cancer tissue that consisted of healthy and cancerous cells.

Researchers noted that when the gold nanoparticles were administered to the body, the body did not reject the particles because they did not produce an immunogenic response and were inert.

After a 12 hour period of incubation, the researchers found that the Gold Nanoparticles made the outer membranes of the cancerous cells rough and easier to penetrate, while not harming the healthy cells.

After the outer membranes of the cancer cells had been altered by gold nanoparticles the researchers administered more gold nanoparticles to the breast tissue.

Now because the first injection of gold nanoparticles altered the membranes of the cancer cells, it allowed the second dosage to pass easily through the cancer cells, which altered the nucleus of the cell, destroying it.

The researchers note that no other type of chemical substance or outside source was necessary to exterminate the diseased cells.

In conclusion at the end of the article, Jimenez Salazar, Professor of the Department of Biology of Reproduction, an expert in gene expression, markers, and molecular signaling stated the following about the outcomes of the research:

""...because the application of chemotherapy causes havoc in organs in a non-specific manner and in that sense the inquiry lays the basis of the creation of substances that attack the tumor cells individually."

See the full article here UAM creates mechanism to destroy breast cancer cells - NTX

'Hairy' Gold Nanoparticles
Kill Cancer with Multiple Punches

The next study comes out of Georgia Tech, where recently a lot of news has been released about their work with Gold Nanoparticles.

The graphic to the left is a light-hearted view of a 'hairy' gold nanoparticle, however all kidding aside, the gold nanoparticles in this study could help save a life one day.

In addition, the 'hairs' on these gold nanoparticles are actually light-sensitive polymers that can assemble and disassemble by using different wavelengths of light.

It was also noted that these 'hairy polymer gold nanoparticles' are made with a core of cancer-fighting drugs.

In the study, once the gold nanoparticles found the cancer cells the light wouldn't only cause the hairs of the polymers attract to each other and bind together, the light would also release the drug to the cancer cell, killing it.

Furthermore, not only did the gold nanoparticles help to deliver the payload of drugs and hairy polymers to the cancer cells, the light also heated the gold nanoparticles which aided the drugs in killing the cancer cells.

See the full article here: New, self-assembled Hairy nanoparticles could give double punch to cancer - Tech Explorist

Gold Nanoparticles Offer New Ways to Fight Kidney Diseases

Every day, our kidney's filter our blood by removing wastes and excess fluid from our bodies, while keeping our blood at its proper PH levels and stabilizing our blood with the right amount of nutrients, electrolytes, and hormones.

The waste is sent to our bladder in the form of urine, while the re-nourished blood is circulated throughout the body.

This next Gold Nanoparticle study comes to us from the University of Texas at Dallas.

A research team, led by Dr. Jie Zheng, associate professor of chemistry in the School of Natural Sciences and Mathematics, studied how the kidneys filtered gold nanoparticles to help them create better therapies to fight kidney diseases.

In the study, they used gold nanoparticles that ranged in size from 1-nanometer and larger.

After conducting their studies, the researchers learned something that wasn't written in their physiology textbooks.

That the smaller gold nanoparticles filtered up to 9x slower than the larger gold nanoparticles.

With this knowledge in hand, the researchers can develop more effective kidney cancer/disease fighting treatments that will stay in the kidney's longer.

See the full article here: Nanoparticle Study Produces Clearer Understanding of Kidney Function - UTD News Center

International Research Study uses Gold Nanoparticles to Kill Cervical Cancer Cells

Cervical Cancer Awareness Gold Nano Ribbon

The last study in this issue of the Gold Nanoparticle Cancer Research News is about how researchers from China, the United States, and Russia used Gold Nanoparticles to transport two chemotherapy drugs to kill HeLa cervical cancer cells.

In this study, researchers synthesized gold nanoparticles and covered or 'decorated' them with two chemotherapy drugs, Bleomycin (BLM) and Doxorubicin (DOX).

These two drugs are known for being effective, but they are also known for having severe side effects.

The stated goal of the study was to "synthesis of AuNPs decorated with two chemotherapy agents and study of their efficiency to carry anti-cancer drug to the tumor site and sustainably cure diseases."

In the study, researchers stated why they used gold nanoparticles:

“Gold nanoparticles (AuNPs), have become highly feasible materials for treating malignant tumors, owing to their unique quenching efficiencies, biocompatibility, and significant surface modifiability.”

Furthermore, the researchers found that once they had coated the gold nanoparticles with Bleomycin (BLM) and Doxorubicin (DOX) that the nanoparticles "exhibit excellent colloidal stability."

In the study, researchers tested Bleomycin (BLM) by itself and compared those results with the results of the gold nanoparticles loaded with BLM and DOX, the following statement was made in the research paper about their findings.

“Based on this comparative analysis, it is feasible to conclude that the combination of the two anticancer therapeutics in the delivery nanovehicle resulted in improved cytotoxic effect at relatively lower concentrations.”

The study proved that by using gold nanoparticles as a 'nano-vehicle' to deliver the two chemotherapy drugs heightened the drug's ability to kill cancer cells in lower dosages.

Which will also result in the fewer side effects from the chemotherapy drugs.

Furthermore, in the conclusion of the study, researchers stated the following on their successful results:

“In light of these results and the “two-punch” approach, we believe that our proposed work offers an excellent opportunity to design nanocarriers with active targeting against ovarian cancer. While improving their bio-distribution and bioavailability profiles in vivo, further studies are envisaged to progress ovarian cancer treatments.”

See the full article here: Gold Nanoparticles-enabled Efficient Dual Delivery of Anticancer Therapeutics to HeLa Cells - Nature.com (Scientific Reports)

One last thing...

To learn more about Gold Nanoparticles and how their specific attributes help kill cancer; 'click here', on the page you’ll learn all there is to know about Gold Nanoparticle Cancer Research

In addition, I recently started The Angel of Healing Cancer Research Fund which supports Gold Nanoparticle Cancer Research, visit this page to learn more about this new fund and the research it supports.

Thank You for your Time.

Take Care & God Bless,

Steve